Avidity of polyreactive immunoglobulins
| Autor: | Bobrovnik Sa |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Ovalbumin
medicine.drug_class Antibody Affinity Immunoglobulins chemical and pharmacologic phenomena Antigen-Antibody Complex Monoclonal antibody Biochemistry lcsh:Biochemistry Mice chemistry.chemical_compound Antigen Antibody Specificity medicine Animals Humans lcsh:QD415-436 Avidity Horses Antigens Serum Albumin biology Myoglobin Antibodies Monoclonal Antibody affinity Molecular biology Kinetics chemistry biology.protein Antibody Chickens Protein Binding |
| Zdroj: | Ukrainian Biochemical Journal, Vol 86, Iss 6, Pp 183-189 (2014) |
| ISSN: | 2409-4943 |
| DOI: | 10.15407/ubj86.06.183 |
| Popis: | An analysis of the mechanism of interaction between polyreactive immunoglobulins (PRIG) and antigen was conducted and it was shown that most of the traditional methods of antibody affinity evaluation are not applicable for PRIG affinity. The comparative assessment of the mouse and human PRIG avidity against ovalbumin and horse myoglobin and the avidity of specific monoclonal antibodies against ovalbumin have shown that the avidity of PRIG not only is much less than the avidity of monoclonal antibodies but even exceeds it. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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