Deceased organ donation in Brazil: how can we improve?
| Autor: | J.O. Medina-Pestana, A.L. Ammirati, E.M. Sampaio, M. Galvao-Pereira, T.H.F. Santos, C.M. Aoqui, D. Caron |
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| Rok vydání: | 2007 |
| Předmět: |
Organ procurement organization
medicine.medical_specialty Brain Death Tissue and Organ Procurement Population Serology medicine Humans Organ donation Registries education Retrospective Studies Transplantation education.field_of_study business.industry Patient Selection Retrospective cohort study Tissue Donors Surgery Heart Arrest Stroke Concomitant Registry data Wounds Gunshot business Brazil |
| Zdroj: | Transplantation proceedings. 39(2) |
| ISSN: | 0041-1345 |
| Popis: | Methods. We retrospectively analyzed the registry data from one organ procurement organization obtained between January 1 and December 31, 2005. Results. Among the 378 potential deceased donors, 182 (48.2%) were lost, mainly due to clinical conditions (27%) or cardiac arrest (19.3%). Of the remaining 196 (51.8%) potential donors, family consent was obtained in 94 cases (48%). Family refusal was higher for potential donors aged between 18 and 59 years (70%). Of the 94 donors, 72 (77%) had their organs harvested. Cardiac arrest before harvesting (56.5%) and positive viral serology (26%) were the main reasons for further losses. The mean donor age was 40 years and 51% were men. Causes of death were cerebral vascular accidents (55.5%), cranium encephalic traumas (29%), and gun shot wounds (8%). The rate of organ donation was 100% for kidneys and livers, 96% for hearts, 86% for pancreatas, 76% for lungs, and 74% for corneas. After assessment of organ viability, 94% of corneas, 91% of kidneys, and 88% of livers were transplanted, but only 52% of pancreata and 42% of hearts. The most frequent causes of discarded organs were age and concomitant donor infection. Conclusion. Areas for potential improvements are: (1) earlier identification and adequate maintenance of potential donors; (2) campaigns for organ donation; and (3) careful evaluation of donated organs and selection of a suitable population to increase utilization of expanded criteria organs. |
| Databáze: | OpenAIRE |
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