Lassa fever in children in Sierra Leone, West Africa
| Autor: | K.M. Johnson, Isabel J. King, R. O'Sullivan, I. Bosman, Luanne H. Elliott, P.A. Webb, Joseph B. McCormick, G.Komba Kono |
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| Rok vydání: | 1986 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent viruses Prevalence Antibodies Viral Sierra Leone West africa Sierra leone Lassa Fever Epidemiology medicine Humans Child Lassa virus Lassa fever business.industry Public Health Environmental and Occupational Health Infant virus diseases General Medicine medicine.disease Virology Infectious Diseases El Niño Child Preschool Immunoglobulin G Vomiting Female Parasitology Viral disease medicine.symptom business |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 80:577-582 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/0035-9203(86)90147-1 |
| Popis: | A systematic study of Lassa fever in febrile children was undertaken over a four-year period, from August 1977 to August 1981, in the Eastern Province of Sierra Leone, West Africa. 479 patients were studied; of these, 245 had adequate specimens to confirm or exclude the laboratory diagnosis of Lassa fever. 51 cases of Lassa fever were identified (21% of patients from whom diagnosis was possible). Virus was isolated from 23 patients. All children had fever; cough and vomiting were present in over 60% of cases studied. The five to nine-year age group had the highest prevalence rate (41% of cases). Seasonal clustering occurred in April, May, and August. A significantly higher proportion of females than males had Lassa fever, a finding which remains to be explained. It is concluded that Lassa fever is a disease of significant concern in the paediatric age group. |
| Databáze: | OpenAIRE |
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