Comparison of the prevalence of antibodies to human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) in Brazil and Colorado
| Autor: | Diana P. Sampaio, Xing-Quan Zhang, Carlos Brites, Roberto Badaró, Lisa Fitzpatrick, Maria de Fatima Melo, Robert T. Schooley, Thomas B. Campbell, Mauro Schechter |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Simplexvirus food.ingredient Colorado Adolescent viruses HIV Infections medicine.disease_cause Antibodies Viral Virus Herpesviridae Serology Cell Line food HIV Seronegativity Epidemiology medicine Prevalence Immunology and Allergy Gammaherpesvirinae Humans Kaposi's sarcoma-associated herpesvirus Homosexuality Male Substance Abuse Intravenous biology business.industry virus diseases Herpesviridae Infections biochemical phenomena metabolism and nutrition Middle Aged biology.organism_classification Virology Infectious Diseases Immunology Herpesvirus 8 Human HIV-1 Female Viral disease business Brazil |
| Zdroj: | The Journal of infectious diseases. 178(5) |
| ISSN: | 0022-1899 |
| Popis: | The prevalence of human herpesvirus 8 (HHV-8; Kaposi's sarcoma [KS] herpesvirus) infection was determined by IFA in 297 persons living in Brazil and Colorado. The prevalence of antibody to HHV-8 in human immunodeficiency virus (HIV) type 1-seropositive gay men with and without KS was similar in Brazil and Colorado. In Brazil, the prevalence of HHV-8 antibody was significantly greater in HIV-1-seronegative gay men than in HIV-1-seronegative male intravenous drug users. HHV-8-seropositive Brazilian gay men who had a clinical diagnosis of KS or who were infected with HIV-1 had significantly higher titers of HHV-8 antibody than did HHV-8-seropositive, HIV-1-seronegative Brazilian gay men. These findings provide further support for the association between HHV-8 infection and KS and suggest that, as in the United States, HHV-8 infection is transmitted sexually in Brazil. |
| Databáze: | OpenAIRE |
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