Estimated Prevalence and Incidence of Dry Eye Disease Based on Coding Analysis of a Large, All-age United States Health Care System
| Autor: | Annie Guerin, Irina Pivneva, Ipek Özer Stillman, John L Bradley, Reza Dana, Debra A. Schaumberg, Amber M. Evans |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Adolescent Population Disease Diagnostic Techniques Ophthalmological 03 medical and health sciences Young Adult 0302 clinical medicine Age Distribution Health care Prevalence Medicine International Statistical Classification of Diseases and Related Health Problems Humans Medical prescription Young adult Sex Distribution education Child 030304 developmental biology Retrospective Studies 0303 health sciences education.field_of_study business.industry Incidence Retrospective cohort study Middle Aged Health Surveys United States Ophthalmology Child Preschool 030221 ophthalmology & optometry Dry Eye Syndromes Female Diagnosis code business Delivery of Health Care Demography Follow-Up Studies |
| Zdroj: | American journal of ophthalmology. 202 |
| ISSN: | 1879-1891 |
| Popis: | Purpose To assess overall prevalence, annual prevalence, and incidence of dry eye disease (DED) in a large, representative population in the United States. Design Prevalence and incidence study. Methods Retrospective analysis using the Department of Defense (DOD) Military Health System (MHS) data on beneficiary medical claims from United States DOD military and civilian facilities, January 1, 2003 through March 31, 2015. Patient Population : Using an algorithm, medical diagnostic codes indicative of DED and prescriptions for cyclosporine ophthalmic emulsion identified a DED population from 9.7 million MHS beneficiaries (DOD service members, retirees, and dependents, aged 2-80+ years). Main Outcome Measures : DED overall prevalence (2003-2015), annual prevalence (2005-2012), and annual incidence (2008-2012) stratified by sex, age group, and International Statistical Classification of Diseases and Related Health Problems, Ninth Revision diagnosis code grouping. Results DED prevalence was 5.28% overall, 7.78% among female beneficiaries, 2.96% among male beneficiaries and increased with age from 0.20% for ages 2-17 years, to 11.66% for individuals aged 50+ years. Annual prevalence increased from 0.8% to 3.0% overall, from 1.4% to 4.5% in female beneficiaries, and from 0.3% to 1.6% in male beneficiaries. Annual prevalence increased across age groups starting at age 18-39, 0.1%-0.6%, to age 50+, 1.8%-6.0%. Annual incidence increased from 0.6% to 0.9% overall, from 0.8% to 1.2% in female beneficiaries, and from 0.3% to 0.6% in male beneficiaries. Across age groups, annual incidence increased starting at age 18-39 (0.2%-0.3%), to age 50+ (1.0%-1.6%). Conclusions DED overall prevalence, annual prevalence, and incidence were found to increase over time for all demographics. These findings highlight the continued importance of research and therapeutic development for this common condition. |
| Databáze: | OpenAIRE |
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