In vitro evaluation of decontamination effects on mechanical properties of fibrin membrane
| Autor: | Alireza Farsinejad, Ahmad Fatemi, Ahmadi ZeydAbadi M, Akbari Saeed T |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Biological phenomena Paint adhesion testing Fibrin 03 medical and health sciences 0302 clinical medicine Tissue engineering Medicine Cell adhesion Decontamination Tissue biology business.industry Membrane Biomaterial General Medicine Sterilization (microbiology) Mechanical phenomena In vitro 030104 developmental biology 030220 oncology & carcinogenesis biology.protein Biophysics Original Article business |
| Zdroj: | Medical Journal of the Islamic Republic of Iran |
| ISSN: | 2251-6840 1016-1430 |
| Popis: | Background: Tissue engineering has been investigated as a potential method for healing traumatized tissues. Biomaterials are material devices or implants used to repair or replace native body tissues and organs. The present study was conducted to evaluate the effects of decontamination methods on biological/mechanical properties and degradation/adhesion test of the platelet-rich fibrin (PRF) membranes to compare these properties with intact membranes as a biological biomaterial. Methods: The in vitro degradation tests were conducted by placing the equal sizes of (i) intact PRF membrane, (ii) PRF membrane sterilized by autoclave (iii), ultraviolet (UV), and (iiii) gamma irradiation in phosphate buffer solution on a shaker. The degradation profiles were expressed. Adhesion test was performed by counting adhered mouse fibroblast and sterilized fibrin membrane was compared to normal fibrin membrane by different sterilization methods. Results: The preliminary findings of sterilized PRF membranes showed that UV exposure (p |
| Databáze: | OpenAIRE |
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