Biodegradable Smart Nanogels: A New Platform for Targeting Drug Delivery and Biomedical Diagnostics
| Autor: | Hai-Qiu Wu, Changchun Wang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Drug Carriers
Computer science Hydrogels Nanotechnology 02 engineering and technology Surfaces and Interfaces 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences Drug delivery Electrochemistry Nanoparticles General Materials Science Nanocarriers 0210 nano-technology Spectroscopy |
| Zdroj: | Langmuir. 32:6211-6225 |
| ISSN: | 1520-5827 0743-7463 |
| DOI: | 10.1021/acs.langmuir.6b00842 |
| Popis: | Nanogels (or nanohydrogels) have been extensively investigated as one of the most promising nanoparticulate biomedical platforms owing to their advantageous properties that combine the characteristics of hydrogel systems with nanoparticles. Among them, smart nanogels that have the ability to respond to external stimuli, such as pH, redox, temperature, enzymes, light, magnetic field and so forth, are most attractive in the area of drug delivery. Besides, numerous multifunctionalized nanogels with high sensitivity and specificity were designed for diagnostic applications. In this feature article, we have reviewed and discussed the recent progress of biodegradable nanogels as smart nanocarriers of anticancer drugs and biomedical diagnostic agents for cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|