Wavefront image sensor chip
Autor: | Changhuei Yang, Jian Ren, Xiquan Cui, Guillermo J. Tearney |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: |
Diagnostic Imaging
Microscope Materials science Aperture Image quality 02 engineering and technology 01 natural sciences law.invention 010309 optics Optics law 0103 physical sciences Image Processing Computer-Assisted Microscopy Interference Microscopy Phase-Contrast Image sensor Oligonucleotide Array Sequence Analysis Wavefront ocis:(010.7350) Wave-front sensing Birefringence business.industry food and beverages ocis:(130.0130) Integrated optics 021001 nanoscience & nanotechnology Atomic and Molecular Physics and Optics Microspheres Amplitude Fresnel number Polystyrenes Research-Article ocis:(110.1220) Apertures 0210 nano-technology business |
Zdroj: | Optics Express |
ISSN: | 1094-4087 |
Popis: | We report the implementation of an image sensor chip, termed wavefront image sensor chip (WIS), that can measure both intensity/amplitude and phase front variations of a light wave separately and quantitatively. By monitoring the tightly confined transmitted light spots through a circular aperture grid in a high Fresnel number regime, we can measure both intensity and phase front variations with a high sampling density (11 microm) and high sensitivity (the sensitivity of normalized phase gradient measurement is 0.1 mrad under the typical working condition). By using WIS in a standard microscope, we can collect both bright-field (transmitted light intensity) and normalized phase gradient images. Our experiments further demonstrate that the normalized phase gradient images of polystyrene microspheres, unstained and stained starfish embryos, and strongly birefringent potato starch granules are improved versions of their corresponding differential interference contrast (DIC) microscope images in that they are artifact-free and quantitative. Besides phase microscopy, WIS can benefit machine recognition, object ranging, and texture assessment for a variety of applications. |
Databáze: | OpenAIRE |
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