Association between lichen sclerosus and celiac disease: a report of three pediatric cases
| Autor: | Dorsey Bass, Lauren Jacobs, Amy Gilliam, M.P.H. Nasim Khavari M.D. |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Population Dermatology Disease Lichen sclerosus Betamethasone Vulvar Lichen Sclerosus Hypopigmented skin lesions Diet Gluten-Free GTP-Binding Proteins Dermatitis herpetiformis Medicine Humans Protein Glutamine gamma Glutamyltransferase 2 education Glucocorticoids education.field_of_study Transglutaminases business.industry Enamel hypoplasia medicine.disease Immunoglobulin A Celiac Disease Child Preschool Pediatrics Perinatology and Child Health Gluten free Female business |
| Zdroj: | Pediatric dermatology. 31(6) |
| ISSN: | 1525-1470 |
| Popis: | The prevalence of celiac disease (CD) is increasing and may be as high as 1% of the US population. The typical presentation of CD generally includes gastrointestinal symptoms, but more individuals are presenting with extraintestinal manifestations. A wide variety of dermatologic associations have been described with CD, including alopecia, dermatitis herpetiformis, and enamel hypoplasia. In this report we describe three girls with CD who presented with hypopigmented skin lesions and pruritus in the perivaginal and perianal areas, consistent with the diagnosis of lichen sclerosus (LS). All three presented within 1 year to the same practitioner. To our knowledge, this association has not previously been explored in the literature. These cases elucidate a possible relationship between CD and LS. |
| Databáze: | OpenAIRE |
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