Impact of body composition on estimated glomerular filtration rate in relatively healthy adults in Taiwan
| Autor: | Jau Yuan Chen, Chih I. Ho, W. C. Li, Ko-Chen Chang, Yi Wen Tsai, Yi Ming Weng, Shou Yen Chen |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Calorie Heart Diseases Taiwan Medicine (miscellaneous) Renal function Physiology urologic and male genital diseases Body Mass Index Sex Factors Metabolic Diseases Sex factors Risk Factors Internal medicine medicine Humans Physical Examination Retrospective Studies Nutrition and Dietetics urogenital system business.industry Smoking Middle Aged medicine.disease Obesity Lipids female genital diseases and pregnancy complications Endocrinology Cross-Sectional Studies Body Composition Female Waist Circumference business Body mass index Glomerular Filtration Rate |
| Zdroj: | European journal of clinical nutrition. 69(1) |
| ISSN: | 1476-5640 |
| Popis: | Chronic kidney diseases are associated with changes in cardiometabolic risk (CMR) factors in which body composition parameters have been used as sensitive predictors. This study aimed to explore the associations of anthropometric indicators, body fat (BF), body mass index (BMI) and waist circumference (WC) with estimated glomerular filtration rate (eGFR) in an adult healthy Chinese population.A cross-sectional study was conducted for the subjects undergoing annual health examinations. The associations of subjects with body composition parameters were analyzed using the cutoff values of BMI, BF and WC in accordance with the criteria for Asian or Taiwanese population by gender.A total of 3473 subjects, aged 30-45 years, who received physical examinations in 2007 were analyzed. The levels of CMR factors were significantly higher in males than in females. eGFR was negatively associated with BMI but positively related to BF. The additional roles of BMI and WC were observed in the subjects who were categorized according to BF. Females with normal weight obese were associated with increased eGFR, whereas a higher eGFR was found in males with low/normal BF and BMI or normal WC.Our data provided evidence that anthropometric parameters were associated with changes of eGFR in relatively healthy adults. Higher eGFR was observed in females with normal weight obese in whom hyperfiltration may be suspected, and this finding deserves further studies. |
| Databáze: | OpenAIRE |
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