The Expanding Spectrum of Eschar-Associated Rickettsioses in the United States
| Autor: | Aaron Z. Hoover, Michael W. Ellis, W. Chad Cragun, William L. Nicholson, Stephen K. Tyring, Brenda L. Bartlett, Marina E. Eremeeva, Ronald P. Rapini, Juan P. Olano, Christopher D. Paddock, Natalia Mendoza, Todd J. Vento |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Endemic Diseases Biopsy Rickettsia rickettsii Dermatology Eschar Diagnosis Differential Rickettsia Infections Humans Medicine Rocky Mountain Spotted Fever Skin biology business.industry General Medicine Middle Aged medicine.disease biology.organism_classification Antibodies Bacterial Texas Virology Rickettsia parkeri Spotted fever Rickettsiosis medicine.symptom business |
| Zdroj: | Archives of Dermatology. 146 |
| ISSN: | 0003-987X |
| Popis: | Background Until recently, Rickettsia rickettsii was the only substantiated cause of tick-borne spotted fever group (SFG) rickettsiosis in humans in the United States. Rickettsia parkeri , originally thought to be nonpathogenic in humans, was recently proved to be another cause of tick-borne SFG rickettsiosis. Observations We report 3 cases of SFG rickettsiosis and discuss the epidemiology, clinical presentation, histopathologic features, and laboratory findings that support confirmed or probable diagnoses of R parkeri infection and describe the expanding list of eschar-associated SFG rickettsioses recognized in US patients. Conclusions The SFG rickettsioses share many clinical manifestations and extensive antigenic cross-reactivity that may hamper specific confirmation of the causative agent. Published online April 19, 2010 (doi:10.1001/archdermatol.2010.48). |
| Databáze: | OpenAIRE |
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