Comments on 'Flexibility of enzymatic transitions as a hallmark of optimized enzyme steady-state kinetics and thermodynamics'
| Autor: | Davor Juretić, Željana Bonačić Lošić |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Flexibility (engineering)
chemistry.chemical_classification Quantitative Biology::Biomolecules Entropy production Chemistry Entropy Quantitative Biology::Molecular Networks Organic Chemistry Thermodynamics Triosephosphate isomerase Information entropy Kinetic flexibility Optimization constraints Thermodynamic dysfunction Biochemistry Quantitative Biology::Subcellular Processes Kinetics Computational Mathematics Enzyme Structural Biology |
| Zdroj: | Computational Biology and Chemistry. 95:107571 |
| ISSN: | 1476-9271 |
| Popis: | System biology advances renewed the interest in enzyme kinetics and the optimization approaches for catalytic performance parameters. We show in this contribution why the maximization of total entropy production is not a good approach for simulating enzyme kinetics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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