Clostridium difficile infection in pediatric patients of oncological hospital: cultivation of anaerobic intestinal flora and treatment

Autor: M. G. Shvydkaya, D. T. Dzhandarova, S. D. Mitrokhin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Microbiology Independent Research Journal, Vol 8, Iss 1, Pp 10-17 (2021)
ISSN: 2500-2236
Popis: In recent years, the number of infectious diseases caused by Clostridium difficile in the world has grown with a significant increase in relapses and mortality in patients, particularly among cancer patients in hospitals. An increase in the resistance of Clostridium difficile to first-line drugs, namely metronidazole and vancomycin, has also been observed and that makes the search for new methods of treatment and the prevention of this infection even more urgent. In this review, we analyze the recent data on the methods of the cultivation and isolation of the pure bacterial culture of Clostridium difficile and other anaerobic enteropathogens over the course of enterocolitis treatment with antimicrobial drugs in pediatric patients with oncopathology. Novel approaches to the therapy of this infection are discussed.
Databáze: OpenAIRE