Age at Menarche and Gallstone Disease in Middle-Aged Women

Autor: Byung Seong Suh, YooJin Kim, Kye Hyun Kim, Hocheol Shin, Eun Chul Chung, Hyun Suk Jung, Juhee Cho, Yoosoo Chang, Bo-Kyoung Kim, Yuni Choi, Min-Jung Kwon, Seungho Ryu, Kyung Eun Yun
Rok vydání: 2016
Předmět:
Zdroj: Reproductive Sciences. 23:1304-1313
ISSN: 1933-7205
1933-7191
DOI: 10.1177/1933719116638187
Popis: The goal of this study was to explore the association between age at menarche and gallstone disease (GSD) in Korean women and to determine whether any of the observed associations were mediated by adult adiposity. A cross-sectional study was performed on 83 275 Korean women, aged 30 years or older, who underwent a health checkup examination between March 2011 and April 2013. Information regarding age at menarche was collected using standardized, self-administered questionnaires. Gallstone disease was defined as either having gallstones or having had a cholecystectomy based on ultrasound. Logistic regression models were used to evaluate the association between age at menarche and GSD. Of the 83 275 women evaluated in this study, 3341 had GSD. Age at menarche was negatively associated with the prevalence of GSD. In a multivariable-adjusted model adjusting for potential confounders including reproductive factors and body weight at age 20, the odds ratios (95% confidence intervals) for GSD comparing menarche at
Databáze: OpenAIRE