Impact of the introduction of an automated microbiologic system on the clinical outcomes of bloodstream infections caused by Enterobacteriaceae strains
| Autor: | Eduardo Alexandrino Servolo Medeiros, Luciana Azevedo Callefi, Guilherme Henrique Campos Furtado |
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| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Bacteremia Outcomes Microbial Sensitivity Tests Diagnostic system Klebsiella spp Teaching hospital Cohort Studies Enterobacteriaceae Internal medicine medicine Humans Mortality Intensive care medicine Retrospective Studies biology Mortality rate Enterobacteriaceae Infections Retrospective cohort study Middle Aged biology.organism_classification Anti-Bacterial Agents Proteus Infectious Diseases Parasitology Female |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 1, Pp 45-49 (2013) Revista da Sociedade Brasileira de Medicina Tropical, Volume: 46, Issue: 1, Pages: 45-49, Published: FEB 2013 Revista da Sociedade Brasileira de Medicina Tropical v.46 n.1 2013 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Volume: 46, Issue: 1, Pages: 45-49, Published: JAN 2013 |
| ISSN: | 1678-9849 |
| Popis: | INTRODUCTION: Enterobacteriaceae strains are a leading cause of bloodstream infections (BSI). The aim of this study is to assess differences in clinical outcomes of patients with BSI caused by Enterobacteriaceae strains before and after introduction of an automated microbiologic system by the microbiology laboratory. METHODS: We conducted a retrospective cohort study aimed to evaluate the impact of the introduction of an automated microbiologic system (Phoenix(tm) automated microbiology system, Becton, Dickinson and Company (BD) - Diagnostic Systems, Sparks, MD, USA) on the outcomes of BSIs caused by Enterobacteriaceae strains. The study was undertaken at Hospital São Paulo, a 750-bed teaching hospital in São Paulo, Brazil. Patients with BSI caused by Enterobacteriaceae strains before the introduction of the automated system were compared with patients with BSI caused by the same pathogens after the introduction of the automated system with regard to treatment adequacy, clinical cure/improvement and 14- and 28-day mortality rates. RESULTS: We evaluated 90 and 106 patients in the non-automated and automated testing periods, respectively. The most prevalent species in both periods were Klebsiella spp. and Proteus spp. Clinical cure/improvement occurred in 70% and 67.9% in non-automated and automated period, respectively (p=0.75). 14-day mortality rates were 22.2% and 30% (p=0.94) and 28-day mortality rates were 24.5% and 40.5% (p= 0.12). There were no significant differences between the two testing periods with regard to treatment adequacy, clinical cure/improvement and 14- and 28-day mortality rates. CONCLUSIONS: Introduction of the BD Phoenix(tm) automated microbiology system did not impact the clinical outcomes of BSIs caused by Enterobacteriaceae strains in our setting. |
| Databáze: | OpenAIRE |
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