8-Chloro-cAMP-Related Changes on Mice Uteri
| Autor: | Andrea Mariel Actis, Levin E, Rosa Bergoc, Máximo Croci |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Medroxyprogesterone mice Article Subject 8-Chloro-cAMP 8-Bromo Cyclic Adenosine Monophosphate lcsh:Medicine Endometrium lcsh:Technology General Biochemistry Genetics and Molecular Biology Estrus Pregnancy Internal medicine medicine Animals Pseudopregnancy lcsh:Science Cystic hyperplasia reproductive and urinary physiology General Environmental Science Estrous cycle Mice Inbred BALB C tamoxifen uterus business.industry urogenital system lcsh:T lcsh:R General Medicine Organ Size medicine.disease medicine.anatomical_structure Endocrinology Endometrial Hyperplasia histopathology Histopathology Female lcsh:Q business Tamoxifen hormones hormone substitutes and hormone antagonists medicine.drug Research Article |
| Zdroj: | The Scientific World Journal, Vol 2, Pp 1426-1432 (2002) The Scientific World Journal |
| Popis: | Histopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight showing cystic hyperplasia and an estral cycle arrested at diestrus. Medroxyprogesterone increased uterine weight, caused a swelling of the endometrium and a pseudopregnancy estrus. When combined with 8-Chloro-cAMP, tamoxifen or medroxyprogesterone always had a predominant effect. We concluded that the effects of 8-Chloro-cAMP on mice uteri did not cause significant changes on its histopathology, but diminished its weight. |
| Databáze: | OpenAIRE |
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