The CAG polymorphism in androgen receptor ( AR ) gene impacts the moral permissibility of harmful behavior in females
| Autor: | Bei Wang, Pengpeng Fang, Wenzhao Ru, Xiaocai Gao, Xing Yang, Jinting Liu, Pingyuan Gong |
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| Rok vydání: | 2017 |
| Předmět: |
Male
China Endocrinology Diabetes and Metabolism Morals 050105 experimental psychology Developmental psychology Judgment Young Adult 03 medical and health sciences 0302 clinical medicine Endocrinology Asian People Gene Frequency Trinucleotide Repeats Polymorphism (computer science) Humans Testosterone 0501 psychology and cognitive sciences Gene Alleles health care economics and organizations Biological Psychiatry S allele Behavior Polymorphism Genetic Endocrine and Autonomic Systems Androgen Receptor Gene 05 social sciences Testosterone (patch) humanities Cag polymorphism Androgen receptor Psychiatry and Mental health Harm Receptors Androgen Androgens Female Psychology 030217 neurology & neurosurgery |
| Zdroj: | Psychoneuroendocrinology. 80:74-79 |
| ISSN: | 0306-4530 |
| DOI: | 10.1016/j.psyneuen.2017.03.008 |
| Popis: | The moral permissibility of harm is strikingly varied among individuals. In light of the connection between testosterone levels and utilitarian moral judgment, this study examined to what extent a CAG polymorphism in the androgen receptor gene, a genetic polymorphism with the ability to regulate testosterone function, contributes to individual differences in moral judgment. Four hundred and thirty-nine Chinese Han participants completed permissibility ratings of harm in moral dilemmas and moral transgression scenarios. Results showed a significant association between the CAG polymorphism and moral permissibility of harm in females. Females with more copies of the S allele, which is associated with higher availability of testosterone, were more likely to judge harmful utilitarian acts and unintentionally harmful acts as permissible, while these effects were absent in males. The findings provide the first evidence for a link between the androgen receptor gene and moral judgment and highlight the role of androgens in moral foundations. |
| Databáze: | OpenAIRE |
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