[Hae RFLP of INHA and its relationship to goat litter size]
| Autor: | Zhong Shen, Qunying Wen, Lin Chen, Liguo Yang, Weisheng Wu, Shi-Lin Chen, Qi-Kang Chen, Guohua Hua, Hong-wei Yao |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Litter (animal)
Genetics Male Polymorphism Genetic Litter Size INHA Accession number (library science) Goats General Medicine Biology Major gene Polymerase Chain Reaction Animals Newborn Genotype Animals Female Inhibins Restriction fragment length polymorphism Allele Polymorphism Restriction Fragment Length Polymorphism Single-Stranded Conformational Genetic association |
| Zdroj: | Yi chuan = Hereditas. 29(8) |
| ISSN: | 0253-9772 |
| Popis: | The polymorphism in a fragment within the coding region of the inhibin a subunit ( INHA ) gene was studied in 323 heads of Matou, Nubi, Boar and Haimen goats by PCR-SSCP, PCR-RFLP and sequencing. A new mutation G284A (Accession number: L28815) was identified, which could be detected by Hae digestion of a PCR product spanning this site. Hae PCR-RFLP analysis indicated that allele G was dominant. Association studies indicated that the effect of INHA genotypes on litter size was greatest for GG, followed by AG and AA genotypes. Thus, INHA may be a major gene controlling the prolificacy of goat, and allele G is positively correlated with litter size. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|