Coeliac disease and autoimmune thyroid disease
| Autor: | W. S. J. Ruddell, C. E. Counsell, Ali S. Taha |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Pathology Letter endocrine system diseases medicine.medical_treatment Hyperthyroidism Thyroglobulin Gastroenterology Coeliac disease Autoimmune Diseases Hypothyroidism Microsomes Internal medicine Immunopathology Prevalence medicine Humans Prospective Studies Prospective cohort study Aged Autoantibodies Aged 80 and over Autoimmune disease business.industry Thyroid disease Thyroid Age Factors nutritional and metabolic diseases Middle Aged medicine.disease Thyroid Diseases digestive system diseases Anti-thyroid autoantibodies Celiac Disease medicine.anatomical_structure Female business Research Article |
| Zdroj: | Gut. 35:844-846 |
| ISSN: | 0017-5749 |
| DOI: | 10.1136/gut.35.6.844 |
| Popis: | A well defined cohort of coeliac patients was studied prospectively to assess the prevalence of coexisting thyroid disease and positive thyroid autoantibodies. Comparison with epidemiological data on the prevalence of coeliac disease in a neighbouring area suggested that few adult coeliac patients had been missed. Overall, 14% of the coeliac patients had thyroid disease: 10.3% were hypothyroid and 3.7% hyperthyroid, both significantly more than expected. There were significantly more coeliac disease patients with thyroid autoantibodies than expected--11% had thyroglobulin antibodies and 15% had thyroid microsomal antibodies. This association is clinically important. Three patients are described in whom the coexistence of coeliac disease and hypothyroidism led to diagnostic difficulties and delay of treatment. |
| Databáze: | OpenAIRE |
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