Fatal poisoning by isoniazid and rifampicin
| Autor: | C Krishnakishore, Y Manjusha, A. V. S. S. N. Sridhar, P Sriramnaveen, Yashawant Sandeep, V Sivakumar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
isoniazid Tuberculosis business.industry Isoniazid Poison control Metabolic acidosis Case Report Fatal poisoning Pharmacology medicine.disease bacterial infections and mycoses rifampicin Gastroenterology Nephrology Internal medicine Lactic acidosis medicine Isoniazid overdose business Rifampicin medicine.drug Red Man Syndrome |
| Zdroj: | Indian Journal of Nephrology |
| ISSN: | 1998-3662 0971-4065 |
| Popis: | Isoniazid and rifampicin are used for management of tuberculosis. Acute poisoning due to isoniazid overdose is associated with repetitive generalized tonic-clonic seizures and severe metabolic acidosis. In toxic doses, rifampicin is known to produce hepatic, renal, hematological disorders, and convulsions. Sometimes, it may produce red man syndrome. We report a case of fatal poisoning with isoniazid and rifampicin. The case was characterized by late presentation, lactic acidosis, and renal failure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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