DAI-1 Receptor Expression in Placenta in Earlyand Late-Onset Preeclampsia
| Autor: | Shchegolev Ai, G. V. Khlestova, M N Nagovitsyna, G. V. Kulikova, N. V. Nizyaeva, M. N. Yushina, O. R. Baev |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
0301 basic medicine Cytoplasm medicine.medical_specialty Placenta Receptor expression Gene Expression Cytoplasmic receptor General Biochemistry Genetics and Molecular Biology Preeclampsia Pathogenesis 03 medical and health sciences 0302 clinical medicine Syncytiotrophoblast Pre-Eclampsia Pregnancy Internal medicine medicine Humans Age of Onset Receptor business.industry Cell Membrane RNA-Binding Proteins General Medicine medicine.disease DNA-Binding Proteins 030104 developmental biology Endocrinology medicine.anatomical_structure Disease Progression Female business Biomarkers 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 164:109-114 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | DAI-1 receptor (DNA-dependent activator of IFN-regulatory factors; DLM-1/ZBP-1) is an innate immunity cytoplasmic receptor of the DNA-recognition receptor class of antiviral immunity. DAI-1 expression reflects the severity of the inflammatory response that plays the key role in the pathogenesis of pregnancy complications. We studied DAI-1 receptor expression in the placental villi in early- and late-onset preeclampsia. In case of early-onset preeclampsia DAI-1 staining intensity was lower (p=0.01), and in case of late preeclampsia - significantly higher (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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