Stage III adenocarcinoma of the endometrium: Two prognostic groups

Autor: William D. Bloomer, James E. Bruckman, Robert C. Knapp, Abraham Marck, Robert L. Ehrmann
Rok vydání: 1980
Předmět:
Zdroj: Gynecologic Oncology. 9:12-17
ISSN: 0090-8258
DOI: 10.1016/0090-8258(80)90003-7
Popis: Between July 1968 and December 1976, 26 patients with surgical-pathologic Stage III adenocarcinoma of the endometrium were treated at the Joint Center for Radiation Therapy. In 15 patients, extrauterine disease was confined to the ovary and/or fallopian tube (Group A). In 11 patients, disease extended beyond these organs to the vagina or other pelvic structures (Group B). Treatment included a combination of radiation therapy and surgery in all but one patient, who was treated by radiation therapy alone. The median follow-up was 65 months and the median time to relapse 9 months. The actuarial relapse-free 5-year survival for all Stage III patients was 54%; it was significantly different ( P = 0.01) for Group A (80%) and Group B (15%). The nature of extrauterine involvement in surgical-pathologic Stage III adenocarcinoma of the endometrium is of major prognostic significance.
Databáze: OpenAIRE