Defecation induced by stimulation of sacral S2 spinal root in cats
| Autor: | Travis Hannan, Jianan Jian, Jonathan M. Beckel, William Wang, Khari Goosby, Zhijun Shen, Christopher Chermansky, Changfeng Tai, Bing Shen, Jicheng Wang, William C. de Groat |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Contraction (grammar) Colon Physiology Rectum Stimulation Physiology (medical) Neuromodulation medicine Animals Defecation Spinal cord injury CATS Hepatology business.industry Lumbosacral Region Gastroenterology Balloon catheter Anatomy medicine.disease Electric Stimulation medicine.anatomical_structure Cats Female Spinal Nerve Roots business |
| Zdroj: | American Journal of Physiology-Gastrointestinal and Liver Physiology. 321:G735-G742 |
| ISSN: | 1522-1547 0193-1857 |
| DOI: | 10.1152/ajpgi.00269.2021 |
| Popis: | The aim of this study was to determine if stimulation of sacral spinal nerve roots can induce defecation in cats. In anesthetized cats, bipolar hook electrodes were placed on the S1-S3 dorsal and/or ventral roots. Stimulus pulses (1-50 Hz, 0.2 ms) were applied to an individual S1-S3 root to induce proximal/distal colon contractions and defecation. Balloon catheters were inserted into the proximal and distal colon to measure contraction pressure. Glass marbles were inserted into the rectum to demonstrate defecation by videotaping the elimination of marbles. Stimulation of the S2 ventral root at 7 Hz induced significantly (p |
| Databáze: | OpenAIRE |
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