Systemic sclerosis with malignant acanthosis nigricans in a patient with gastric adenocarcinoma
| Autor: | Sabina Sandigursky, Daniel A. Nadelman, David E Orbuch, Alisa N. Femia |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
systemic sclerosis Case Report Dermatology Disease Intertriginous Capecitabine 030207 dermatology & venereal diseases 03 medical and health sciences Gastric adenocarcinoma 0302 clinical medicine medicine Acanthosis nigricans acanthosis nigricans SSc systemic sclerosis integumentary system business.industry gastric cancer Cancer medicine.disease 030220 oncology & carcinogenesis Malignant acanthosis nigricans paraneoplastic business Sudden onset medicine.drug |
| Zdroj: | JAAD Case Reports |
| ISSN: | 2352-5126 |
| DOI: | 10.1016/j.jdcr.2019.10.003 |
| Popis: | Systemic sclerosis (SSc) is an idiopathic sclerosing condition that may affect both the skin and internal organs.1 Although SSc has been associated with an increase in the development of malignant neoplasms, the disease can present in a paraneoplastic manner months to years after initial cancer diagnosis in rare cases.1,2 Malignant acanthosis nigricans is a rare paraneoplastic skin syndrome that presents with sudden onset of hyperpigmented velvety plaques, most commonly in intertriginous areas. Here, we report a case of newly acquired SSc and acanthosis nigricans in a patient with a 2-year history of gastric adenocarcinoma being treated with capecitabine. |
| Databáze: | OpenAIRE |
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