Exploring the Source of Neural Responses of Different Latencies Obtained from Different Recording Electrodes in Cochlear Implant Users
| Autor: | Akinori Kashio, Rachel A. Scheperle, Carolyn J. Brown, Paul J. Abbas, Viral D. Tejani |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Materials science Adolescent Physiology medicine.medical_treatment 0206 medical engineering Action Potentials 02 engineering and technology Audiology Article Young Adult 03 medical and health sciences Speech and Hearing 0302 clinical medicine Cochlear implant Reaction Time medicine Humans Auditory system Latency (engineering) Child 030223 otorhinolaryngology Electrodes Cochlea Aged Neurons Remote recording Middle Aged Cochlear Implantation 020601 biomedical engineering Electric Stimulation Sensory Systems Compound muscle action potential Cochlear Implants medicine.anatomical_structure Otorhinolaryngology Child Preschool Electrode Evoked Potentials Auditory Female Communication channel |
| Zdroj: | Audiology and Neurotology. 21:141-149 |
| ISSN: | 1421-9700 1420-3030 |
| Popis: | In this study we measured the electrically evoked compound action potential (ECAP) from different recording electrodes in the cochlea. Under the assumption that different response latencies may be the result of differences in the neural population contributing to the response, we assessed the relationship between neural response latency and spread of excitation. First, we evaluated changes in N1 latency when the recording electrode site was varied. Second, we recorded channel interaction functions using a forward masking technique but with recording electrodes at different intracochlear locations. For most individuals, N1 latency was similar across recording electrodes. However, reduced N1 latencies were observed in 21% of cochlear implant users when ECAPs were recorded using a remote recording electrode. We hypothesized that if recordings from different electrodes represented contributions from different populations of neurons, then one might expect that channel interaction functions would be different. However, we did not observe consistent differences in channel interaction functions (neither peak location nor breadth of the functions), and further, any variation in channel interaction functions was not correlated with ECAP latency. These results suggest that ECAPs from different recording electrodes with different latencies originate from similar neural populations. |
| Databáze: | OpenAIRE |
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