Metabolic syndrome: pathophysiology, management, and modulation by natural compounds
| Autor: | Swathi Kovelamudi, Yogita Rochlani, Naga Venkata Pothineni, Jawahar L. Mehta |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Anti-Inflammatory Agents Reviews Disease 030204 cardiovascular system & hematology Bioinformatics Pathogenesis 03 medical and health sciences 0302 clinical medicine Insulin resistance Predictive Value of Tests Risk Factors Internal medicine Diabetes mellitus Epidemiology medicine Humans Pharmacology (medical) Risk factor Inflammation Metabolic Syndrome business.industry medicine.disease Obesity Early Diagnosis Treatment Outcome 030104 developmental biology Endocrinology Dietary Supplements Metabolic syndrome Cardiology and Cardiovascular Medicine business |
| Zdroj: | Therapeutic Advances in Cardiovascular Disease. 11:215-225 |
| ISSN: | 1753-9455 1753-9447 |
| DOI: | 10.1177/1753944717711379 |
| Popis: | Metabolic syndrome (MetS) represents a cluster of metabolic abnormalities that include hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia, and is strongly associated with an increased risk for developing diabetes and atherosclerotic and nonatherosclerotic cardiovascular disease (CVD). The pathogenesis of MetS involves both genetic and acquired factors that contribute to the final pathway of inflammation that leads to CVD. MetS has gained significant importance recently due to the exponential increase in obesity worldwide. Early diagnosis is important in order to employ lifestyle and risk factor modification. Here, we review the epidemiology and pathogenesis of MetS, the role of inflammation in MetS, and summarize existing natural therapies for MetS. |
| Databáze: | OpenAIRE |
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