Hemorheological parameters in patients with fibromyalgia syndrome

Autor: Gokhan Caglayan, Sibel Bayrak, Neslihan Dikmenoglu Falkmarken, Okan Arihan, Ayşen Akıncı
Přispěvatelé: [Arihan, Okan] Yuzuncu Yil Univ, Fac Med, Dept Physiol, Van, Turkey -- [Caglayan, Gokhan] Cumhuriyet Univ, Fac Med, Dept Phys & Rehabil Med, Div Rheumatol, Sivas, Turkey -- [Bayrak, Sibel -- Falkmarken, Neslihan Dikmenoglu] Hacettepe Univ, Fac Med, Dept Physiol, Ankara, Turkey -- [Akinci, Aysen] Hacettepe Univ, Fac Med, Dept Phys & Rehabil Med, Ankara, Turkey
Rok vydání: 2017
Předmět:
Adult
Erythrocyte Aggregation
Male
musculoskeletal diseases
erythrocyte deformability
medicine.medical_specialty
Fibromyalgia
Physiology
Blood viscosity
030204 cardiovascular system & hematology
Fibrinogen
Gastroenterology
Erythrocyte aggregation
03 medical and health sciences
0302 clinical medicine
Erythrocyte Deformability
Physiology (medical)
Internal medicine
medicine
Humans
Erythrocyte deformability
hemorheology
reproductive and urinary physiology
030203 arthritis & rheumatology
medicine.diagnostic_test
business.industry
Albumin
Complete blood count
hemic and immune systems
Syndrome
Hematology
Middle Aged
Blood Viscosity
biological factors
Hemorheology
embryonic structures
blood viscosity
Female
plasma viscosity
fibromyalgia
erythrocyte
Cardiology and Cardiovascular Medicine
Lipid profile
business
medicine.drug
Zdroj: Clinical Hemorheology and Microcirculation. 65:309-315
ISSN: 1875-8622
1386-0291
DOI: 10.3233/ch-16160
Popis: WOS: 000400599300001
PubMed ID: 27814281
AIM: To evaluate hemorheological parameters in patients with fibromyalgia syndrome (FMS) in order to elucidate the etiology of the disease. METHODS: Twenty-three adult FMS patients and 20 healthy controls were enrolled in the study. Diabetics, hypertensives and those with any rheumatological disorder or use drugs or smoking cigarette were excluded from the study. Following parameters were analyzed in each subject; erythrocyte deformability, erythrocyte aggregation, plasma viscosity, complete blood count, fasting blood glucose, fibrinogen, albumin, globulin and lipid profile. RESULTS: Erythrocyte elongation indices indicating deformability of erythrocytes were higher in FMS patients (0.564 +/- 0.002 at 16.87mPa and 0.605 +/- 0.002 at 30mPa shear rate) than controls (0.558 +/- 0.001 at 16.87mPa and 0.600 +/- 0.003 at 30mPa shear rate). Erythrocyte aggregation speed was higher in FMS patients (2.1 +/- 0.1 s) than controls (2.3 +/- 0.2 s). Erythrocyte aggregation index was also higher in FMS patients (65.5 +/- 1.3) than controls (62.9 +/- 1.5). Erythrocyte aggregation amplitude and plasma viscosity values were similar in both groups (both p > 0.05). Among the complete blood count and biochemical parameters, only albumin levels were lower in the FM patients than controls (p < 0.05). CONCLUSION: Our results indicate higher erythrocyte deformability and quicker erythrocyte aggregation in FM patients.
Hacettepe University Scientific Research Administration
This study was supported by Hacettepe University Scientific Research Administration.
Databáze: OpenAIRE
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