Estimation of genetic distances between 'reeler' and nearby loci on mouse chromosome 5
| Autor: | D. Ruelle, André M. Goffinet, Christiane Dernoncourt |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
Recombination Genetic Genetics Mice Inbred BALB C biology Breakpoint Chromosome Mapping Chromosome Genes Recessive Chromosomal translocation biology.organism_classification BALB/c Mice Inbred C57BL Mice Reeler Gene mapping Central Nervous System Diseases Mutation Backcrossing Animals Female lipids (amino acids peptides and proteins) Gene Crosses Genetic |
| Zdroj: | Genomics. 11:1167-1169 |
| ISSN: | 0888-7543 |
| DOI: | 10.1016/0888-7543(91)90049-k |
| Popis: | Genetic distances between reeler (gene symbol rl ) and the adjacent loci Pgy-1, Sor , and En-2 on proximal chromosome 5 were estimated using a backcross panel between rl Orl rl Orl BALB c and C57 mice. Pgy-1 and Sor are located ≈7 cM away from and centromeric to reeler , whereas En-2 is located distally, ≈8 cM from reeler . Backcrosses between rl Orl rl Orl BALB c and mice with the T31H translocation showed that the breakpoint is located less than 2 cM from reeler . Together with previous work, these observations suggest the following gene order: Cen - Sor Pgy -1-rl-T31H-En-2- other loci. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|