C-reactive protein as an aid in the differentiation of functional and inflammatory bowel disorders
| Autor: | B. Shine, Louise Berghouse, J.E.Lennard Jones, J. Landon |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
medicine.medical_specialty Pathology Clinical Biochemistry Physical examination Disease Blood Sedimentation Colonic Diseases Functional Biochemistry Gastroenterology Diagnosis Differential Crohn Disease Internal medicine medicine Outpatient clinic Humans Crohn's disease medicine.diagnostic_test biology business.industry Biochemistry (medical) C-reactive protein General Medicine Orosomucoid medicine.disease Elevated erythrocyte sedimentation rate Ulcerative colitis digestive system diseases C-Reactive Protein Erythrocyte sedimentation rate biology.protein Colitis Ulcerative business |
| Zdroj: | Clinica chimica acta; international journal of clinical chemistry. 148(2) |
| ISSN: | 0009-8981 |
| Popis: | Eighty-two patients were investigated on their first visit to the outpatient department of St. Mark's Hospital, London, for the assessment of abdominal symptoms. In addition to the clinical examination, a rectal biopsy, routine tests and appropriate special investigations, blood was taken from each patient for the determination of erythrocyte sedimentation rate, C-reactive protein and alpha-1-acid glycoprotein. Nineteen patients were finally diagnosed as having Crohn's disease, twenty-two ulcerative colitis, and forty-one functional bowel disorders. All the patients with Crohn's disease had an elevated erythrocyte sedimentation rate and C-reactive protein level as had 11 (50%) of the patients with ulcerative colitis, but none with functional disorders. All cases of ulcerative colitis could be diagnosed by rectal biopsy. Measurement of alpha-1-acid glycoprotein provided no additional diagnostic information. A combination of rectal biopsy, and measurement of the erythrocyte sedimentation rate and C-reactive protein successfully distinguishes between inflammatory disease of the large and small bowel and functional bowel syndrome. |
| Databáze: | OpenAIRE |
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