Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes

Autor: J. Oleske, J. Mendelson, M. Tardieu, L. Hoyt, M. Mintz, G. McSherry
Rok vydání: 1996
Předmět:
Zdroj: Neurology. 47:1583-1585
ISSN: 1526-632X
0028-3878
Popis: Five children with human immunodeficiency virus type-1 (HIV-1) infection, aged 4 to 13 years, manifested extrapyramidal dysfunction characterized by rigidity/stiffness, ambulation difficulties/shuffling gait, dysarthria/drooling/swallowing dysfunction, hypomimetic/inexpressive facies, and bradykinesia. Levodopa therapy caused an initial improvement in all symptoms, and the effect was sustained in most patients. Levodopa is a useful adjunctive therapy in HIV-1-infected children with extrapyramidal syndromes, by enhancing motor function and improving their quality of life. NEUROLOGY 1996;47: 1583-1585
Databáze: OpenAIRE