Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes
Autor: | J. Oleske, J. Mendelson, M. Tardieu, L. Hoyt, M. Mintz, G. McSherry |
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Rok vydání: | 1996 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Levodopa Neurology medicine.medical_treatment HIV Infections Drooling Dysarthria Swallowing Acquired immunodeficiency syndrome (AIDS) medicine Humans Chemotherapy Movement Disorders business.industry Syndrome medicine.disease nervous system diseases El Niño Child Preschool Physical therapy Female Neurology (clinical) medicine.symptom business medicine.drug |
Zdroj: | Neurology. 47:1583-1585 |
ISSN: | 1526-632X 0028-3878 |
Popis: | Five children with human immunodeficiency virus type-1 (HIV-1) infection, aged 4 to 13 years, manifested extrapyramidal dysfunction characterized by rigidity/stiffness, ambulation difficulties/shuffling gait, dysarthria/drooling/swallowing dysfunction, hypomimetic/inexpressive facies, and bradykinesia. Levodopa therapy caused an initial improvement in all symptoms, and the effect was sustained in most patients. Levodopa is a useful adjunctive therapy in HIV-1-infected children with extrapyramidal syndromes, by enhancing motor function and improving their quality of life. NEUROLOGY 1996;47: 1583-1585 |
Databáze: | OpenAIRE |
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