Perianal mucinous adenocarcinoma with dysplastic polyps of the colon: A case report
| Autor: | Alberto Porcu, Antonio Mario Scanu, Maria Laura Cossu, Claudio F. Feo, Simone Veneroni, Giorgio Carlo Ginesu, Antonio Santoru |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Anal fistula
medicine.medical_specialty Rectum Disease Colonic polyps 03 medical and health sciences 0302 clinical medicine Endoanal ultrasound Case report medicine medicine.diagnostic_test business.industry Magnetic resonance imaging Anal canal medicine.disease digestive system diseases medicine.anatomical_structure 030220 oncology & carcinogenesis Etiology Adenocarcinoma 030211 gastroenterology & hepatology Surgery Radiology business Mucinous adenocarcinoma |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • Mucinous adenocarcinoma of the perianal region is extremely rare (6.9% of anal neoplasms and 2–3% of all gastrointestinal malignancies). • Given the low incidence of this tumor, it is often missed at initial evaluation. • Association with chronic perianal fistula are common and inflammatory symptoms can be misleading with delay in diagnosis. • The paucity of publications leads to a lack of consensus on both diagnostic and therapeutic approaches. • The understanding of the etiopathogenic mechanisms may lead to the development of novel diagnostic and therapeutic protocols. Introduction Perianal mucinous adenocarcinoma is rarely encountered in the setting of anal neoplasms. The rarity of the disease and the paucity of publications on this topic are responsible for a lack of diagnostic and therapeutic guidelines. Presentation of case An 80-year-old man with mucinous adenocarcinoma of the anal canal associated with dysplastic polyps of the colon was treated by multiple endoscopic polypectomies and abdomino-perineal resection of the rectum. We discuss the management of this rare case from the diagnosis up to one-year follow-up. Discussion Perianal mucinous adenocarcinoma is a very rare entity frequently combined with chronic fistulas. Inflammatory symptoms may mislead its diagnosis, which is often delayed. The unique association between perianal mucinous adenocarcinoma and dysplastic polyps of the colon, that we have reported, may suggest a secondary etiology. High clinical suspicion is important for early and correct diagnosis, which should be based on endoanal ultrasound and/or magnetic resonance imaging followed by deep tissue biopsies. Conclusion We stress the importance of accumulating such cases in the literature. The understanding of the etiopathogenic mechanisms may lead to the development of novel diagnostic and therapeutic protocols. |
| Databáze: | OpenAIRE |
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