Fasciculations and their F-response revisited: high-density surface EMG in ALS and benign fasciculations
| Autor: | Helenius J. Schelhaas, Ilse M.P. Arts, Dick F. Stegeman, Bert U. Kleine, Werner A. Boekestein, Machiel J. Zwarts |
|---|---|
| Přispěvatelé: | Kinesiology, Research Institute MOVE |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Benign condition DCN MP - Plasticity and memory education Action Potentials High density Progressive neurodegeneration Audiology Fasciculation Gastrocnemius muscle SDG 3 - Good Health and Well-being Physiology (medical) Reaction Time medicine Humans Amyotrophic lateral sclerosis Muscle Skeletal Aged Electromyography Amyotrophic Lateral Sclerosis Benign fasciculations Middle Aged medicine.disease Sensory Systems Human Movement & Fatigue DCN PAC - Perception action and control [NCEBP 10] Neurology Female Neurology (clinical) Radiology medicine.symptom Psychology |
| Zdroj: | Clinical Neurophysiology, 123, 2, pp. 399-405 Kleine, B U, Boekestein, W A, Arts, I M, Zwarts, M J, Schelhaas, H J & Stegeman, D F 2012, ' Fasciculations and their F-response revisited: High-density surface EMG in ALS and benign fasciculations ', Clinical Neurophysiology, vol. 123, no. 2, pp. 399-405 . https://doi.org/10.1016/j.clinph.2011.06.032 Clinical Neurophysiology, 123, 399-405 Clinical Neurophysiology, 123(2), 399-405. International Federation of Clinical Neurophysiology |
| ISSN: | 1388-2457 |
| DOI: | 10.1016/j.clinph.2011.06.032 |
| Popis: | Objective: To compare the prevalence of fasciculation potentials (FPs) with F-responses between patients with amyotrophic lateral sclerosis (ALS) and patients with benign fasciculations. Methods: In seven patients with ALS and seven patients with benign fasciculations, high-density surface EMG was recorded for 15. min from the gastrocnemius muscle. Template matching was used to search for pairs of FPs with a repetition within 10-110. ms. Results: Interspike interval (ISI) histograms were constructed from 282 pairs of benign fasciculations and from 337 FP pairs in ALS. Peaks attributable to F-waves were found at latencies of 32. ms (benign) and 35. ms (ALS). Five patients with benign fasciculations and four patients with ALS had FPs with F-waves. Conclusions: F-waves of FPs occur in both conditions - therefore they are not diagnostically helpful. Significance: F-waves confirm the distal origin of FPs for an individual axon. The occurrence of these FPs in a benign condition suggests that the generation of ectopic discharges in the distal axons is not specific to progressive neurodegeneration. © 2011 International Federation of Clinical Neurophysiology. |
| Databáze: | OpenAIRE |
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