Cardiometabolic and Mental Health in Women With Early Gestational Diabetes Mellitus: A Prospective Cohort Study

Autor: Leah Gilbert, Emmanuel Cosson, Dan Yedu Quansah, Justine Gross, Jardena J. Puder, Katrien Benhalima, Antje Horsch, Amelie Pauchet
Rok vydání: 2021
Předmět:
Time Factors
Endocrinology
Diabetes and Metabolism
Clinical Biochemistry
Biochemistry
0302 clinical medicine
Endocrinology
Pregnancy
Prevalence
Prospective Studies
030212 general & internal medicine
Prediabetes
Prospective cohort study
Metabolic Syndrome
Obstetrics
Postpartum Period
Gestational age
Metabolic syndrome
Gestational Weight Gain
3. Good health
Gestational diabetes
Cardio-metabolic
Mental Health
Cardiovascular Diseases
Mental health
Female
Adult
Cardiometabolic Risk Factors
Cardiovascular Diseases/epidemiology
Case-Control Studies
Diabetes
Gestational/epidemiology
Diabetes
Gestational/metabolism
Follow-Up Studies
Glucose Tolerance Test
Humans
Mental Health/statistics & numerical data
Metabolic Syndrome/epidemiology
Metabolic Syndrome/metabolism
Postpartum Period/metabolism
Postpartum Period/psychology
Prediabetic State/epidemiology
Prediabetic State/metabolism
GDM risk factors
cardiometabolic
early gestational diabetes
mental health
metabolic syndrome
postpartum
medicine.medical_specialty
030209 endocrinology & metabolism
Context (language use)
Prediabetic State
03 medical and health sciences
Postpartum
Diabetes mellitus
Internal medicine
medicine
Early gestational diabetes
business.industry
Biochemistry (medical)
medicine.disease
Diabetes
Gestational
GDM-risk factors
business
Zdroj: The Journal of clinical endocrinology and metabolism, vol. 107, no. 3, pp. e996-e1008
ISSN: 1945-7197
0021-972X
DOI: 10.1210/clinem/dgab791
Popis: Context Early diagnosis and treatment of gestational diabetes (GDM) may reduce adverse obstetric and neonatal outcomes, especially in high-risk women. However, there is a lack of data for other outcomes. Objective We compared cardiometabolic and mental health outcomes in women with early (eGDM) and classical (cGDM) GDM. Methods This prospective cohort included 1185 All women with cGDM and 76 women with eGDM. The eGDM group had GDM risk factors (BMI >30 kg/m2, family history of diabetes, history of GDM, ethnicity), were tested at Results The eGDM group had lower gestational weight gain than cGDM (10.7 ± 6.2 vs 12.6 ± 6.4; P = 0.03) but needed more medical treatment (66% vs 42%; P Conclusion Compared with cGDM, eGDM was not associated with differences in mental health, but with increased adverse cardiometabolic outcomes, independent of GDM risk factors and gestational weight gain. This hints to a preexisting risk profile in eGDM.
Databáze: OpenAIRE
Externí odkaz: