Rabies in a set of eight-week old puppies in Nigeria: the need for review of current dog antirabies vaccination schedule
| Autor: | Ishaya Sini Tekki, Utibe-Abasi Hilary Udoh, David Shamaki, Okon John Ifut, Emmanuel O. Ngbede, Udoh Akpan Inyang, Ponfa Nden Zhakom, Philip A. Okewole, Pam Dachung Luka, Lami H. Lombin, Philip Paul Mshelbwala, Nsika Joseph Ekanem, Nanven A. Maurice, Magdalene Nanven Maurice |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Pediatrics Rabies Vaccination schedule 030231 tropical medicine 030106 microbiology RT-PCR Nigeria Article DFAT 03 medical and health sciences 0302 clinical medicine Rabies Virus Antigen medicine Direct fluorescent antibody Puppies business.industry Public health medicine.disease DRIT Infectious Diseases Immunization Immunohistochemical Test business |
| Zdroj: | African Journal of Infectious Diseases; Vol 12, No 2 (2018); 72-77 African Journal of Infectious Diseases |
| ISSN: | 2006-0165 |
| Popis: | Background: Rabies is endemic in Nigeria with clinical cases reported mainly in dogs and occasionally in livestock from all the geo-ecological zones of the country. Detection of rabies virus antigen in puppies at the age of five to ten weeks and in apparently healthy dogs shedding the virus in their saliva have been reported in some parts of Nigeria.Material and Method: This report describes a clinical rabies in a set of eight weeks old puppies confirmed by antigen detection using the direct fluorescent antibody test (DFAT), the direct rapid immunohistochemical test (DRIT), and RT-PCR.Results: it was positive for all test used including the RT-PCR which amplified at 750 bp from the gel electrophoresis.Conclusion: Occurrence of rabies in puppies of this age, within which they are acquired and owned by other unsuspecting members of the public, is of grave public health consequences. People that love puppies, especially children, who are fond of carrying and playing with them, are also faced with the risk of exposure to rabies. Consequently, review of the existing dog antirabies vaccination schedule at twelve weeks of age in Nigeria, is recommended to ensure effective immunization of this age group of dogs and for the overall safety of the vulnerable members of the public.Keywords: Puppies, Rabies, Vaccination schedule, DFAT, DRIT, RT-PCR, Nigeria |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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