Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios of overweight children and adolescents

Autor: Luisa Gonzalles Yazaki, João Carlos Pina Faria, Fabíola Isabel Suano de Souza, Roseli Oselka Saccardo Sarni
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Revista da Associação Médica Brasileira, Volume: 68, Issue: 8, Pages: 1006-1010, Published: 19 SEP 2022
Revista da Associação Médica Brasileira v.68 n.8 2022
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Popis: SUMMARY OBJECTIVE: This study aimed to compare neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio of overweight children and adolescents with the eutrophic ratios and to verify whether these ratios are associated with age, inflammation, Z-score of body mass index, and waist-to-height ratio. METHODS: This is a cross-sectional study involving 64 overweight and 106 eutrophic children and adolescents. Data on weight, height, and waist circumference (body mass index and waist-to-height ratio), blood count (neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio), and high-sensitivity C-reactive protein were collected. RESULTS: The mean age of participants was 8.4±3.2 years. The ratios did not differ between the overweight and non-overweight groups. The platelet-to-lymphocyte ratio has shown a direct and independent association with body mass index (p=0.031) and waist-to-height ratio (p=0.018), a fact not observed for neutrophil-to-lymphocyte ratio. The ultrasensitive C-reactive protein level was higher in the obesity group (p=0.003). Both ratios had a direct and independent association with age. CONCLUSION: The ratios did not differ between the overweight and non-overweight groups. There was a direct and independent association of platelet-to-lymphocyte ratio with overweight, not observed in neutrophil-to-lymphocyte ratio. The ratios have significantly increased according to the age of the participants.
Databáze: OpenAIRE
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