Quantitative Coronary Angiographic and Intravascular Ultrasound Assessment of a New Nonarticulated Stent: Report From the Advanced Cardiovascular Systems MultiLink Stent Pilot Study
Autor: | Donald S. Baim, Jeffrey J. Popma, Richard E. Kuntz, Gary S. Roubin, Kalon K.L. Ho, Linda K. Robertson, James B. Hermiller, Larry S. Dean, Joseph P. Carrozza, Thomas J. Linnemeier, Paul G. Yock, Donald E. Cutlip |
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Rok vydání: | 1998 |
Předmět: |
Coronary angiography
Male medicine.medical_specialty medicine.medical_treatment Treatment outcome Optimal deployment Coronary Disease Pilot Projects Coronary disease Coronary Angiography Internal medicine Intravascular ultrasound medicine Humans cardiovascular diseases Ultrasonography Interventional Aged medicine.diagnostic_test business.industry Stent Equipment Design Middle Aged medicine.disease equipment and supplies Coronary heart disease Stenosis Treatment Outcome surgical procedures operative Cardiology Feasibility Studies Female Stents Radiology business Cardiology and Cardiovascular Medicine |
Zdroj: | Journal of the American College of Cardiology. 31(1):50-56 |
ISSN: | 0735-1097 |
DOI: | 10.1016/s0735-1097(97)00426-9 |
Popis: | Objectives. The purpose of this study was to evaluate the safety, feasibility, optimal deployment technique and 1-year clinical outcome for the Advanced Cardiovascular Systems (ACS) MultiLink stent.Background. Optimal stent deployment assessed by quantitative coronary angiography and intravascular ultrasound (IVUS) is associated with improved clinical outcome.Methods. Forty-nine consecutive patients with a discrete stenosis in a native coronary artery 3 to 4 mm in diameter were treated with the new, balloon-expandable ACS MultiLink stent. Stent expansion was assessed in all patients using quantitative coronary angiography and serial IVUS imaging after 8-, 12- and 16-atm inflations. Clinical follow-up was obtained at 30 days and 1 year.Results. All 49 patients had successful placement of a MultiLink stent without death, emergency coronary artery bypass graft surgery or Q wave myocardial infarction. After placement of the MultiLink stent, the minimal lumen diameter increased from 1.24 to 2.98 mm (p < 0.001), and diameter stenosis decreased from 61% to 7% (p = 0.001). Minimal lumen cross-sectional area by IVUS increased progressively after 8, 12 and 16 atm (5.6 to 6.8 to 7.4 mm2, respectively, p < 0.001). However, only 64% of stents achieved a lumen/reference area ratio ≥70%. No adverse clinical events occurred by 30 days, and by 1 year only one patient (2.0%) required revascularization of the stented artery.Conclusions. Treatment of stenoses in native coronary arteries with the MultiLink stent is associated with a high success rate and a low incidence of adverse events by 1 year, despite the fact that the majority of stents did not meet IVUS-defined criteria for “optimal stenting” derived from first-generation devices. |
Databáze: | OpenAIRE |
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