The Effect of Atromid on Fibrinolytic Activity of Patients with Ischaemic Heart Disease and Hypercholesterolaemia
| Autor: | M.J. Smith, S.C. Srivastava, H.A. Dewar |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
medicine.medical_specialty
Androsterone business.industry Hypercholesterolemia Coronary Disease Coronary Artery Disease General Medicine Serum cholesterol level Coronary disease Gastroenterology Surgery Butyrates chemistry.chemical_compound Whole Blood Clot Lysis Time chemistry Internal medicine medicine Humans Ischaemic heart disease Clofibrate business Blood Coagulation Serum cholesterol |
| Zdroj: | Journal of Atherosclerosis Research. 3:640-647 |
| ISSN: | 0368-1319 |
| DOI: | 10.1016/s0368-1319(63)80047-2 |
| Popis: | Summary (1) Eighteen patients suffering from ischaemic heart disease and whose fasting serum cholesterol was at or above 300 mg/100 ml have been treated with Atromid and their serum cholesterol and whole blood clot lysis time studied serially over a 5-month period. (2) The fibrinolytic activity of this group of patients was significantly lower than that of healthy young controls and this activity correlated inversely with the serum cholesterol level. (3) Atromid lowered the serum cholesterol within 1 month by a mean of 102 mg/ 100 ml (27 % reduction) and this was maintained over the next 4 months. (4) The fibrinolytic activity was enhanced Pari passu with the reduction in serum cholesterol by a mean increase of 7 units (43 %) and there was a statistically significant correlation between these 2 parameters. |
| Databáze: | OpenAIRE |
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