Suprachiasmatic circadian pacemaker of rat shows two windows of sensitivity to neuropeptide Y in vitro
| Autor: | Martha U. Gillette, Marija Medanic |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
genetic structures Light Central nervous system Hypothalamus Biology In Vitro Techniques Slice preparation Geniculate medicine Animals Neuropeptide Y Circadian rhythm Molecular Biology Neurons Dose-Response Relationship Drug Suprachiasmatic nucleus General Neuroscience Darkness Neuropeptide Y receptor humanities Circadian Rhythm Rats Electrophysiology medicine.anatomical_structure Light effects on circadian rhythm Suprachiasmatic Nucleus sense organs Neurology (clinical) Neuroscience Developmental Biology |
| Zdroj: | Brain research. 620(2) |
| ISSN: | 0006-8993 |
| Popis: | The geniculohypothalamic tract carries visual information from the intergeniculate leaflet to the suprachiasmatic circadian pacemaker. NPY, found in this projection, has been shown to affect the phase of behavioral rhythms and influence photic entrainment. We now demonstrate that NPY, when briefly applied to the geniculate projection sites of rat SCN in vitro, induces permanent phase-shifts in the rhythm of neuronal electrical activity at two separate phases of the circadian cycle. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|