Gastric juice ammonia vs CLO test for diagnosis of Helicobacter pylori infection
| Autor: | Jong Sun Rew, Young Eun Joo, Chong Mann Yoon, Dae Hyun Yang, Sung Kyu Choi, Hee Seung Bom |
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| Rok vydání: | 1995 |
| Předmět: |
Male
medicine.medical_specialty Physiology Spirillaceae Biopsy Chronic gastritis Gastroenterology Sensitivity and Specificity Helicobacter Infections Ammonia chemistry.chemical_compound Stomach Neoplasms Internal medicine medicine Humans Stomach Ulcer Gastric Juice biology medicine.diagnostic_test Receiver operating characteristic Helicobacter pylori business.industry Stomach Hepatology Middle Aged biology.organism_classification medicine.disease Urease medicine.anatomical_structure chemistry ROC Curve Gastric Mucosa Duodenal Ulcer Gastritis Female Reagent Kits Diagnostic business |
| Zdroj: | Digestive diseases and sciences. 40(5) |
| ISSN: | 0163-2116 |
| Popis: | The aim of the present study was to compare the gastric juice ammonia test to the CLO test for the diagnosis of H. pylori infection in culture-proven cases by receiver operating characteristic (ROC) curve analysis. We studied 75 subjects (44 with chronic gastritis, 10 with gastric ulcer, 6 with duodenal ulcer, 8 with gastric cancer, and 7 normal) by endoscopy with biopsy for tissue diagnosis, culture of H. pylori. CLO test, and by gastric juice ammonia determinations. The culture-positive group had significantly higher intragastric ammonia levels (13.7 +/- 5.8 mg/dl) than the negative group (4.9 +/- 2.4 mg/dl, P0.01). In ROC curve analysis, the gastric juice ammonia test showed higher true positive and lower false positive ratios than the CLO test (P0.05). In conclusion, the measurement of intragastric juice ammonia levels was considered to be simpler, quicker, and overall a more valuable method for diagnosing H. pylori infection. |
| Databáze: | OpenAIRE |
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