Asymptomatic Atherosclerosis in Egyptian Rheumatoid Arthritis Patients and Its Relation to Disease Activity
| Autor: | Aymen F Darwish, Mohammed Abdel-kadar, Rawhya R. El-Shereef, Lamiaa Hamdy, Amal Ali |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pathology lcsh:Diseases of the musculoskeletal system medicine.diagnostic_test Article Subject business.industry Immunology Physical examination Disease medicine.disease Gastroenterology Asymptomatic Disease activity Rheumatology Rheumatoid arthritis Internal medicine medicine.artery medicine Medical history medicine.symptom Brachial artery lcsh:RC925-935 business Wall thickness Research Article |
| Zdroj: | International Journal of Rheumatology, Vol 2015 (2015) International Journal of Rheumatology |
| ISSN: | 1687-9279 1687-9260 |
| Popis: | Aim. To detect the frequency of subclinical atherosclerosis in rheumatoid arthritis patients without clinically evident atherosclerosis and to correlate its presence with the disease activity.Patients and Methods. Our study includes 112 RA patients (group 1) and 40 healthy controls (group 11). All patients and controls were subjected to full history taking, clinical examination, and laboratory investigations. Carotid intima media wall thickness (IMT) and carotid plaques were measured in both groups by B-mode ultrasonography; also color duplex Doppler ultrasound of the brachial artery was done to detect endothelial function.Results. There is atherosclerosis in 31.3% of asymptomatic RA patients compared with only 5% in controlsP=0.003**. A significant difference was detected in patients with and without atherosclerosis regarding duration of the diseaseP=0.0001***and patient’s ageP=0.01*. There is highly statistical significant correlation between atherosclerosis and disease activity index.Conclusion. The frequency of subclinical atherosclerosis was high in long-term active RA patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|