Delirium, depression, and long-term cognition
| Autor: | Chelsea Rick, Jennifer L. Thompson, Warren D. Taylor, Eugene Wesley Ely, Amy L. Kiehl, Jo Ellen Wilson, Rameela Raman, Patricia Andrews, Pratik P. Pandharipande, James C. Jackson |
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| Rok vydání: | 2023 |
| Předmět: |
medicine.medical_specialty
Repeatable Battery for the Assessment of Neuropsychological Status business.industry Cognition Intensive care unit Article law.invention Psychiatry and Mental health Clinical Psychology law Internal medicine medicine History of depression Delirium Effects of sleep deprivation on cognitive performance Geriatrics and Gerontology medicine.symptom Cognitive impairment business Gerontology Depression (differential diagnoses) |
| Zdroj: | Int Psychogeriatr |
| ISSN: | 1741-203X 1041-6102 |
| Popis: | Objectives: We examined whether preadmission history of depression is associated with less delirium/coma-free (DCF) days, worse 1-year depression severity and cognitive impairment. Design and measurements: A health proxy reported history of depression. Separate models examined the effect of preadmission history of depression on: (a) intensive care unit (ICU) course, measured as DCF days; (b) depression symptom severity at 3 and 12 months, measured by the Beck Depression Inventory-II (BDI-II); and (c) cognitive performance at 3 and 12 months, measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) global score. Setting and participants: Patients admitted to the medical/surgical ICU services were eligible. Results: Of 821 subjects eligible at enrollment, 261 (33%) had preadmission history of depression. After adjusting for covariates, preadmission history of depression was not associated with less DCF days (OR 0.78, 95% CI, 0.59–1.03 p = 0.077). A prior history of depression was associated with higher BDI-II scores at 3 and 12 months (3 months OR 2.15, 95% CI, 1.42–3.24 p = p = 0.003). We did not observe an association between preadmission history of depression and cognitive performance at either 3 or 12 months (3 months beta coefficient −0.04, 95% CI, −2.70–2.62 p = 0.97; 12 months 1.5, 95% CI, −1.26–4.26 p = 0.28). Conclusion: Patients with a depression history prior to ICU stay exhibit a greater severity of depressive symptoms in the year after hospitalization. |
| Databáze: | OpenAIRE |
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