Somatosensory and auditory processing in opioid-exposed newborns with neonatal abstinence syndrome: a magnetoencephalographic approach
| Autor: | Sarimari Tupola, Satu Kivitie-Kallio, Päivi Nevalainen, Elina Pihko, Kaisa Kivistö, Leena Lauronen |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Auditory Pathways Central nervous system Gestational Age Audiology Somatosensory system 03 medical and health sciences 0302 clinical medicine Neonatal abstinence Pregnancy Evoked Potentials Somatosensory 030225 pediatrics medicine Humans Maternal-Fetal Exchange Fetus medicine.diagnostic_test business.industry Infant Newborn Magnetoencephalography Obstetrics and Gynecology medicine.disease Buprenorphine Analgesics Opioid medicine.anatomical_structure Opioid Anesthesia Pediatrics Perinatology and Child Health Evoked Potentials Auditory Somatosensory Disorders Female business Neonatal Abstinence Syndrome 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | JOURNAL OF MATERNAL-FETAL AND NEONATAL MEDICINE. 28(17):2015-2019 |
| ISSN: | 1476-7058 |
| DOI: | 10.3109/14767058.2014.978755 |
| Popis: | Opioid exposure during pregnancy is a potential risk factor for the developing central nervous system of the fetus. We studied evoked responses in buprenorphine-exposed newborns who displayed neonatal abstinence syndrome (NAS) to elucidate the possible alterations in functioning of the somatosensory and auditory systems.We compared somatosensory (SEFs) and auditory evoked magnetic fields (AEFs), recorded with magnetoencephalography (MEG), of 11 prenatally buprenorphine-exposed newborns with those of 12 healthy newborns. Peak latencies, source strength and location of SEFs or AEFs were recorded.AEFs were present in all buprenorphine-exposed newborns without significant differences from those of healthy newborns. In contrast, though no group level differences in SEFs existed, at individual level the response deviated from the typical neonatal morphology in four buprenorphine-exposed newborns.Although buprenorphine exposure during pregnancy does not seem to cause constant deficiencies in somatosensory or auditory processing, in some newborns the typical development of somatosensory networks may be - at least transiently - disrupted. |
| Databáze: | OpenAIRE |
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