Endoscopic removal of nucleus pulposus of intervertebral disc on lumbar intervertebral disc protrusion and the influence on inflammatory factors and immune function
| Autor: | Xiaojun Li, Zhou Pinghui, Zhengqi Bao, Changchun Zhang, Kun Zhu, Gang Xu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty medicine.medical_treatment 03 medical and health sciences inflammatory factors 0302 clinical medicine Immune system Immunology and Microbiology (miscellaneous) Discectomy endoscopic removal of nucleus pulposus of intervertebral disc Medicine Inflammatory factors Lumbar intervertebral disc immune function business.industry Incidence (epidemiology) Therapeutic effect lumbar intervertebral disc protrusion Intervertebral disc Articles General Medicine Surgery 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis business Surgical incision |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2019.8223 |
| Popis: | Endoscopic removal of nucleus pulposus (NP) of intervertebral disc (IVD) on lumbar intervertebral disc protrusion (LIDP) and its influence on inflammatory factors and immune function were explored. A total of 145 patients with LIDP admitted to The First Affiliated Hospital of Bengbu Medical College from June 2017 to December 2018 were selected and electively treated, in which 87 patients were treated with fenestration discectomy (fenestration group) and 58 patients were treated with endoscopic removal of NP of IVD (minimally invasive group). Effects on patients in the two groups within 6 months after surgery were evaluated by modified MacNab score; differences in surgical related indexes and incidence rates of complications between the two groups were compared; the Oswestry dysfunction score and VAS pain score before treatment, and 1, 3 and 6 months after treatment, and changes of cellular levels of TNF-α, IL-4, IL-6, CD3+, CD4+, and CD8+ before treatment, and 24 and 48 h after surgery were evaluated. Length of surgical incision, intraoperative blood loss, time of operation, time in bed, and hospital stays of patients in minimally invasive group were lower than those in the fenestration group (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|