The importance of ganglion cell complex investigation in myopic patients
Autor: | Catalina Corbu, Miruna Burcel, Maria Veronica Strehaianu, Dana Dascalescu, Catalina Ionescu, Vasile Potop |
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Rok vydání: | 2018 |
Předmět: |
Retinal Ganglion Cells
medicine.medical_specialty genetic structures Optic Disk Nerve fiber layer Glaucoma Nerve fiber Case Reports Optic neuropathy chemistry.chemical_compound Nerve Fibers Optical coherence tomography ganglion cell complex Ophthalmology medicine Myopia Humans Intraocular Pressure medicine.diagnostic_test business.industry Retinal General Medicine medicine.disease eye diseases Ganglion medicine.anatomical_structure glaucoma chemistry sense organs business Tomography Optical Coherence Optic disc |
Zdroj: | Romanian Journal of Ophthalmology |
ISSN: | 2457-4325 |
Popis: | Glaucoma is an optic neuropathy that affects the ganglion cell complex in all its components: cell bodies, dendrites, and axons, the dendritic arbor being the first one damaged. This is the reason why the thickness of the ganglion cell and internal plexiform layers can be taken into account as an early predictor of the glaucomatous changes, along with the retinal nerve fiber layer (RNFL) thickness. However, due to disc tilting and peripapillary atrophy, the RNFL evaluation may be prone to errors in myopic patients. We presented the cases of two myopic patients, who, after a routine examination, were identified as glaucoma suspects. The Optical Coherence Tomography (OCT) scan revealed a nerve fiber loss which was not confirmed by the ganglion cell complex scan. Thereafter we manually adjusted the optic disc margins according to the patients' myopic changes and this time the retinal nerve fiber layer was also normal. We observed that the ganglion cell complex evaluation led to fewer errors than the retinal nerve fiber layer evaluation, particularly in front of a myopic patient. Nevertheless, various investigations should be considered in the attempt to issue a diagnosis of glaucoma. |
Databáze: | OpenAIRE |
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