Human papillomavirus infection of the lower female genital tract: association with multicentric neoplasia
| Autor: | Butler Eb, Stanbridge Cm |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Female circumcision
Adult Pathology medicine.medical_specialty Vaginal Neoplasms Adolescent Genital Neoplasms Female Biopsy Uterine Cervical Neoplasms Biology Virus Pathology and Forensic Medicine Pregnancy medicine Animals Humans Human papillomavirus Papillomaviridae Intraepithelial neoplasia Vulvar Neoplasms Obstetrics and Gynecology Condyloma Acuminatum medicine.disease Pregnancy Complications Microscopy Electron Tumor Virus Infections Renal transplant Female Viral disease Neoplasm Recurrence Local Genital Diseases Female |
| Zdroj: | International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2(3) |
| ISSN: | 0277-1691 |
| Popis: | Fifty-four patients with multiple condylomatous lesions and/or multicentric neoplasia were identified in a consecutive series of 2,627 colposcopic examinations (2%). Forty-one percent presented with condylomata only and 57% exhibited associated intraepithelial or invasive neoplasia in at least one site. Only one patient was found to have multicentric neoplasia with no condylomatous features. There was a significant increase in mean age between patients presenting with multiple condylomatous lesions and those who had intraepithelial neoplasia as well. An association with pregnancy was found in 17% of the cases, and with renal transplant in 5%. Virus particles compatible with human papillomavirus were found in 62% of the cases examined. Evidence for a causative role in the development of neoplasia of the lower female genital tract is considered. |
| Databáze: | OpenAIRE |
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