| Autor: |
Francisco Gama, Stefania Rosmini, Steve Bandula, Kush P. Patel, Paolo Massa, Catalina Tobon-Gomez, Karolin Ecke, Tyler Stroud, Mark Condron, George D. Thornton, Jonathan B. Bennett, Ashutosh Wechelakar, Julian D. Gillmore, Carol Whelan, Helen Lachmann, Stuart A. Taylor, Francesca Pugliese, Marianna Fontana, James C. Moon, Philip N. Hawkins, Thomas A. Treibel |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
JACC: Cardiovascular Imaging. 15:2082-2094 |
| ISSN: |
1936-878X |
| Popis: |
Light chain (AL) and transthyretin (ATTR) amyloid fibrils are deposited in the extracellular space of the myocardium, resulting in heart failure and premature mortality. Extracellular expansion can be quantified by computed tomography, offering a rapid, cheaper, and more practical alternative to cardiac magnetic resonance, especially among patients with cardiac devices or on renal dialysis.This study sought to investigate the association of extracellular volume fraction by computed tomography (ECVPatients with confirmed systemic amyloidosis and varying degrees of cardiac involvement underwent electrocardiography-gated cardiac computed tomography. Whole heart and septal ECVA total of 72 patients were studied (AL: n = 35, ATTR: n = 37; median age: 67 [IQR: 59-76] years, 70.8% male). Mean septal ECVCardiac amyloid burden quantified by ECV |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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