Oscillatory flow and quasi-steady behavior in a model of human central airways
| Autor: | G. G. Berdine, Jeffrey M. Drazen, Arthur S. Slutsky |
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| Rok vydání: | 1981 |
| Předmět: |
Models
Anatomic Physics Time Factors Physiology Flow distribution Airway Resistance Respiration Mechanics Inertance Models Structural Physics::Fluid Dynamics Flow (mathematics) Physiology (medical) Distortion Quasi steady Pressure Range (statistics) Humans Asymmetric distribution Mathematics Oscillatory flow |
| Zdroj: | Journal of Applied Physiology. 50:1293-1299 |
| ISSN: | 1522-1601 8750-7587 |
| Popis: | We studied biased oscillatory flow in a model of human central airways to examine under what conditions oscillatory flow deviated from steady flow. Although the steady flow resistance of the model was 25% less than the oscillatory flow resistance of the model at 15Hz, the overall inertance of the model did not change over the range of frequencies from 5 to 15 Hz, suggesting that frequency-dependent inertial distortion of velocity profiles did not alter central airway pressure-flow relationships over this frequency range. In a given terminal branch of the model, instantaneous oscillatory flow at 2 and 5 Hz could be predicted well from the steady flow distribution, but with increasing frequency the oscillatory flow from the branch deviated more from the steady flow predictions. A significant component of this deviation was due to a phase shift between predicted and measured oscillatory flow. We conclude that the major frequency-dependent behavior flow in the human central airways is a phasic redistribution of flow above 7 Hz, resulting from the asymmetric distribution of inertances in this structure. |
| Databáze: | OpenAIRE |
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