Edmonton Symptom Assessment Scale and Clinical Characteristics Associated With Cannabinoid Use in Oncology Supportive Care Outpatients
| Autor: | Jae-Woo Jung, Sahana Rajasekhara, Joshua Smith, Vijay Desai, Meghan Haas, Jongphil Kim, Kristine A. Donovan, Diane Portman, Young D. Chang, Ritika Oberoi-Jassal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Oncology
Adult Male medicine.medical_specialty Palliative care Nausea medicine.medical_treatment Population Symptom assessment Medical Oncology Article 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine Statistical significance Neoplasms mental disorders Ambulatory Care Odds Ratio Medicine Drug test Humans 030212 general & internal medicine Practice Patterns Physicians' education Aged Retrospective Studies Aged 80 and over education.field_of_study medicine.diagnostic_test business.industry Cannabinoids Palliative Care Middle Aged Drug Utilization Quartile 030220 oncology & carcinogenesis Female Cannabinoid medicine.symptom business |
| Zdroj: | J Natl Compr Canc Netw |
| Popis: | Background: Information about the frequency of cannabinoid use and the clinical characteristics of its users in oncology supportive care is limited. This study explored associations between cannabinoid use and cancer-related clinical characteristics in a cancer population. Patients and Methods: This retrospective review included 332 patients who had a urine drug test (UDT) for tetrahydrocannabinol (THC) together with completion of an Edmonton Symptom Assessment Scale (ESAS) and cannabinoid history questionnaire on the same day that urine was obtained during 1 year in the supportive care clinic. Results: The frequency of positive results for THC in a UDT was 22.9% (n=76). Significant statistical differences were seen between THC-positive and THC-negative patients for age (median of 52 [lower quartile, 44; upper quartile, 56] vs 58 [48; 67] years; PP=.034), and past or current cannabinoid use (65.8% vs 26.2%; PP=.001), nausea (1 [0; 3] vs 0 [0; 3]; P=.049), appetite (4 [2; 7] vs 3 [0; 5.75]; P=.015), overall well-being (5.5 [4; 7] vs 5 [3; 6]; P=.002), spiritual well-being (5 [2; 6] vs 3 [1; 3]; P=.015), insomnia (7 [5; 9] vs 4 [2; 7]; PP=.001). Among patients who reported current or past cannabinoid use, THC-positive patients had higher total scores and scores for pain, appetite, overall well-being, spiritual well-being, and insomnia than THC-negative patients. Conclusions: Patients with cancer receiving outpatient supportive care who had positive UDT results for THC had higher symptom severity scores for pain, nausea, appetite, overall and spiritual well-being, and insomnia compared with their THC-negative counterparts. These results highlight potential opportunities to improve palliative care. |
| Databáze: | OpenAIRE |
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