Studies on urea cycle enzyme levels in the human fetal liver at different gestational ages
Autor: | Habibullah Cm, Mallappa Kumara Swamy, Mukarram Ali Baig M, Hassan I, Devi Bg, Taher-uz-Zaman, Ayesha Q |
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Rok vydání: | 1992 |
Předmět: |
Adult
Male medicine.medical_specialty Argininosuccinate synthase Carbamoyl-Phosphate Synthase (Ammonia) Gestational Age Biology Argininosuccinate Synthase chemistry.chemical_compound Fetus Internal medicine medicine Humans Urea Ornithine Carbamoyltransferase Arginase Gestational age Argininosuccinate lyase Argininosuccinate Lyase Enzyme assay Endocrinology chemistry Liver Pediatrics Perinatology and Child Health biology.protein Gestation Female |
Zdroj: | Pediatric research. 31(2) |
ISSN: | 0031-3998 |
Popis: | Urea cycle enzymes involved in the detoxification of ammonia were studied in liver tissues of 57 male and 49 female fetuses of different age groups ranging from 13 to 36 wk of gestation. Surgical wedge biopsies of liver from 18 male and 12 female adults were used as controls. Significant enzyme activity was found to be present as early as the 13th wk of gestation. As gestational age advanced, enzyme activity gradually increased, reaching about 90% of the adult activity by the 36th wk of gestation. |
Databáze: | OpenAIRE |
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