Maternal and Neonatal Effects of Substance Abuse during Pregnancy : Our Ten-year Experience
| Autor: | Zoran Vucinovic, Damir Roje, Marija Bucat, Mirjana Vučinović, Ivo Banović, Vesna Čapkun |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Croatia Birth weight neonatal outcome Illicit drug Pregnancy Infant Mortality medicine Birth Weight Humans Pregnancy Complications Infectious pregnancy outcome business.industry Obstetrics Heroin Dependence Incidence Infant Newborn General Medicine medicine.disease Infant mortality Substance abuse Heroin Pregnancy Complications Low birth weight Maternal Exposure Apgar Score Gestation Apgar score Original Article Female medicine.symptom business Neonatal Abstinence Syndrome Methadone medicine.drug |
| Zdroj: | Yonsei Medical Journal |
| Popis: | Purpose The aim of the study was to assess perinatal outcome of pregnancy burdened with maternal addiction in comparison with an unselected population from a European transition country. Materials and Methods Data on pregnancies complicated by illicit drug abuse (n = 85) managed during a 10-year period (1997 - 2007) at Split University Hospital were analyzed. Data on the type of drug, course of gestation and labor, and on perinatal outcome were considered. Data on all non-dependence pregnancies recorded during the study period were used as a control group. Results During the study period, there were 85 dependence-complicated pregnancies (0.2%). Use of heroin alone during pregnancy was recorded in 51 women (50%), methadone alone in 6 (7%), and a combination of heroin and methadone in 9 (11%). Premature delivery was significantly more common in the group of pregnant addicts (21% vs. 6%) ; 49% of pregnant addicts were carriers of hepatitis C virus (HCV) and 14% of hepatitis B virus (HBV). Neonatal abstinence syndrome developed in 61 infants (7%) born to addicted mothers. There were 4 cases (4.6%) of early neonatal death ; 7 neonates had 5-minute Apgar score ≤ 7 (8%) ; 29 neonates had low birth weight for age (33%) ; and 7 neonates had congenital anomalies (8%). The risk of various congenital anomalies was 3-fold in the group of children born to addicted mothers. Conclusion Addiction pregnancies present a small but high-risk group according to perinatal outcome. Appropriate obstetric and neonatal care can reduce the rate of complications in these pregnancies and improve perinatal outcome. |
| Databáze: | OpenAIRE |
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